genus Actinonaias Crosse & Fischer, 1894: 5 Recent species.
synonymy (2 available nomina) | 8 species
Distribution: Central America

genus Arotonaias Martens, 1900: 4 Recent species.
synonymy (3 available nomina) | 4 species
Distribution: Central America

genus Atlanticoncha Smith, Pfeiffer & Johnson, 2020: 1 Recent species.
synonymy (1 available nomina) | 1 species
Distribution: North America

genus Cambarunio Watters, 2018: 7 Recent species.
synonymy (1 available nomina) | 7 species
Distribution: North America

genus Cyprogenia Agassiz, 1852: 2 Recent species.
synonymy (1 available nomina) | 2 species
Distribution: North America

genus Cyrtonaias Crosse & Fischer, 1894: 1 Recent species.
synonymy (1 available nomina) | 1 species
Distribution: North America

genus Delphinonaias Crosse & Fischer, 1894: 2 Recent species.
synonymy (2 available nomina) | 2 species
Distribution: Central America

genus Disconaias Crosse & Fischer, 1894: 3 Recent species.
synonymy (2 available nomina) | 3 species
Distribution: North America, Central America

genus Dromus Simpson, 1900: 1 Recent species.
synonymy (3 available nomina) | 1 species
Distribution: North America

genus Ellipsaria Rafinesque, 1820: 1 Recent species.
synonymy (3 available nomina) | 1 species
Distribution: North America

genus Epioblasma Rafinesque, 1831: 28 Recent species.
synonymy (9 available nomina) | 29 species
Distribution: North America

genus Friersonia Ortmann, 1912: 1 Recent species.
synonymy (1 available nomina) | 1 species
Distribution: Central America

genus Glebula Conrad, 1853: 1 Recent species.
synonymy (1 available nomina) | 1 species
Distribution: North America

genus Hamiota Roe & Hartfield, 2005: 4 Recent species.
synonymy (1 available nomina) | 4 species
Distribution: North America

genus Lampsilis Rafinesque, 1820: 26 Recent species.
synonymy (3 available nomina) | 34 species
Distribution: North America

genus Leaunio Watters, 2018: 5 Recent species.
synonymy (1 available nomina) | 5 species
Distribution: North America

genus Lemiox Rafinesque, 1831: 1 Recent species.
synonymy (2 available nomina) | 2 species
Distribution: North America

genus Ligumia Swainson, 1840: 1 Recent species.
synonymy (1 available nomina) | 9 species
Distribution: North America

genus Medionidus Simpson, 1900: 6 Recent species.
synonymy (1 available nomina) | 7 species
Distribution: North America

genus Mesonaias Crosse & Fischer, 1894: 3 Recent species.
synonymy (1 available nomina) | 3 species
Distribution: Central America

genus Obliquaria Rafinesque, 1820: 1 Recent species.
synonymy (1 available nomina) | 1 species
Distribution: North America

genus Obovaria Rafinesque, 1819: 7 Recent species.
synonymy (5 available nomina) | 7 species
Distribution: North America

genus Ortmanniana Frierson, 1927: 2 Recent species.
synonymy (1 available nomina) | 2 species
Distribution: North America

genus Pachynaias Crosse & Fischer, 1894: 1 Recent species.
synonymy (1 available nomina) | 1 species
Distribution: Central America

genus Paetulunio Watters, 2018: 1 Recent species.
synonymy (2 available nomina) | 1 species
Distribution: North America

genus Potamilus Rafinesque, 1818: 10 Recent species.
synonymy (11 available nomina) | 11 species
Distribution: North America, East Asia

genus Ptychobranchus Simpson, 1900: 6 Recent species.
synonymy (3 available nomina) | 8 species
Distribution: North America

genus Sagittunio Watters, 2018: 4 Recent species.
synonymy (1 available nomina) | 4 species
Distribution: North America

genus Toxolasma Rafinesque, 1831: 7 Recent species.
synonymy (3 available nomina) | 7 species
Distribution: North America

genus Truncilla Rafinesque, 1819: 4 Recent species.
synonymy (2 available nomina) | 4 species
Distribution: North America

genus Venustaconcha Frierson, 1927: 5 Recent species.
synonymy (2 available nomina) | 5 species
Distribution: North America

genus Villosa Frierson, 1927: 4 Recent species.
synonymy (1 available nomina) | 4 species
Distribution: North America